Personal profile
Education
Biology/Anatomy, Ph.D., University of Puerto Rico
General Sciences, B.S., University of Puerto Rico
Scholarly Contributions
- 15 Article
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PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficits
Walsh, L. J., Espinal-San Miguel, I. M., Rodriguez, A. V., Peña, U. M., Flynn, K. E., Remillard, W. C., Brazier, S. R., Anderson, N. I., Clark, A. J., De Varona, T. A., Soto, I. & Soto Reyes, I., 2025, In: Unknown journal. 15, 1, p. 24460Research output: Contribution to journal › Article
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Role of mTORC1 signaling in postnatal microglia activation preceding neurodegeneration in a mouse model for Niemann-Pick disease Type C
Murray, C. E., Betancourt-Trompa, D. S., Martinez, M. S., Carson, J. M., Walsh, L. J., Remillard, W. C., Fordyce, K. B., Reddy, R., Soto, I. & Soto Reyes, I., 2025, In: Unknown journal. 20, 9, p. e0330437Research output: Contribution to journal › Article
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Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease
Kim, S., Ochoa, K., Melli, S. E., Yousufzai, F. A. K., Barrera, Z. D., Williams, A. A., McIntyre, G., Delgado, E., Bolish, J. N., Macleod, C. M., Boghos, M., Lens, H. P., Ramos, A. G., Wilson, V. B., Maloney, K., Padron, Z. M., Khan, A. H., Blanco, R. E., Soto, I. & Soto Reyes, I., 2023, In: Unknown journal. 13, 1, p. 5665Research output: Contribution to journal › Article
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Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo
MacLeod, C. M., Yousufzai, F. A. K., Spencer, L. T., Kim, S., Rivera-Rosario, L. A., Barrera, Z. D., Walsh, L., Krummenacher, C., Carone, B., Soto, I. & Soto Reyes, I., 2023, In: Unknown journal. 18, 11, p. e0294312Research output: Contribution to journal › Article
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NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick disease type C
Boyle, B. R., Melli, S. E., Altreche, R. S., Padron, Z. M., Yousufzai, F. A. K., Kim, S., Vasquez, M. D., Carone, D. M., Carone, B. R., Soto, I. & Soto Reyes, I., 2020, In: Unknown journal. 147, 21Research output: Contribution to journal › Article
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CAREER: Metabolic control of Purkinje Cell dendritic development and mouse behavior
Soto Reyes, I. (PI)
04/1/20 → 03/31/26
Project: Research